ISSN: 2168-9296
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Duo Zhang
Tanzania
Mini Review
Extracellular Vesicles Facilitate the Intercellular Communications in the Pathogenesis of Lung Injury
Author(s): Heedoo Lee, Duo Zhang, Jasleen Minhas and Yang Jin
Heedoo Lee, Duo Zhang, Jasleen Minhas and Yang Jin
Extracellular vesicles (EVs) are a group of heterogeneous, nano-sized structures surrounded by lipid bilayer membranes that are released by cells. Depending on their size and mechanisms of formation, EVs are often referred to as exosomes, microvesicles (MVs) and apoptotic bodies (AB). EVs are evolutionally conserved vesicles that mediate intercellular communications and cross-talk, via transferring proteins, lipids and nucleic acids. Accumulating evidence suggests that EVs exert essential physiological and pathological functions on both their mother and recipient cells. Therefore, growing interests focus on the potentials of EVs to serve as novel targets for the development of therapeutic and diagnostic strategies. Currently, extensive reports are yielded from cancer research. However, besides malignancy, EVs may also serve as crucial regulators in other devastating conditions, such a.. View More»
DOI:
10.4172/2168-9296.1000175