Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Éva Somogyiné-Vári
Hungary
Research Article
The Prevalence and Characteristics of Allergy in Autoimmune Thyroid Diseases
Author(s): Ildikó Molnár, Erzsébet Kelemen and Éva Somogyiné-VáriIldikó Molnár, Erzsébet Kelemen and Éva Somogyiné-Vári
Objective: The relationship between autoimmunity and allergy is well known. The immunoregulation can be modified towards T helper 2 dominance by cytokines and regulatory T cells, which participate in both diseases. Autoimmune thyroid diseases possess different immunoregulatory and sympathoadrenal activity, whose features can be reflected by their association with allergic attacks and the degree of allergen-specific IgE levels. Methods: Two-hundred-fifty-nine patients, 149 with Graves’ disease (57 had ophthalmopathy), 110 with Hashimoto’s thyroiditis and 65 controls with small euthyroid goitre were investigated. Allergen-specific IgE levels to 20 respiratory and 20 food allergens were detected by AllergySreen immunoblot method and given in IU/ml. Thyroid hormones and autoantibodies to thyroid peroxidase (T.. View More»
DOI:
10.4172/2155-9899.1000306