Biochemistry & Pharmacology: Open Access
Open Access

Egbeolu O

Publications

• Research Article
  Assessment of the Prophylactic Activity of the Ethanolic Extract of Momordica charantia Leaves against Acetaminophen-Induced Liver Impairment in Wistar Rats
  Author(s): Abiola T*, Akinyode OA, Oduwole R and Egbeolu O Abiola T*, Akinyode OA, Oduwole R and Egbeolu O
  
  Background: Various parts of M. charantia have been reported to possess pharmacological properties against some diseases due to its phytochemicals constituents. Aim: This research was aimed at assessing the prophylactic effect of the ethanol extract of M. charantia against acetaminophen-induced liver damage in Wistar rats. Methodology: A total of sixteen rats were randomly divided into four groups with four rats in each group. The experiment spanned through fourteen days. Group 1 served as the control, group 2 received 1500 mg/kg per body weight (pbw) of acetaminophen orally throughout, group 3 received 250 mg/kg (pbw) of extract throughout while group 4 received 250 mg/kg (pbw) of extract for six days and thereafter was given 1500 mg/kg (pbw) acetaminophen orally from day 7 to day 14. The biochem.. View More»
  DOI: 10.4172/2167-0501.1000230

  Abstract PDF

Relevant Topics