ISSN: 2155-9570
Elena Ciuffoletti
Italy
Research Article
Automatic Segmentation of Posterior Pole Retinal Layers In Patients with Early Stage Glaucoma Using Spectral Domain Optical Coherence Tomography
Author(s): Massimo Cesareo, Elena Ciuffoletti, Alessio Martucci, Carlo Balducci, Andrea Cusumano, Federico Ricci and Roberto Pietro Sorge
Massimo Cesareo, Elena Ciuffoletti, Alessio Martucci, Carlo Balducci, Andrea Cusumano, Federico Ricci and Roberto Pietro Sorge
Purpose: To measure Ganglion Cell Layer (GCL) and Retinal Nerve Fiber Layer (RNFL) thickness of the retinal posterior pole in patients with early stage primary open-angle glaucoma (POAG) using the new automatic segmentation technology of spectral domain optical coherence tomograph (SD-OCT). Methods: 37 clinical records of patients with early glaucoma (grade 1 to 2 according to the Glaucoma Staging System 2) and 40 age and sex-matched controls were considered in this case-control observational retrospective study. Automated segmentation of GCL and RNFL was performed in one randomly selected eye from the electronic OCT records of each participant using the new Spectralis SD-OCT segmentation technology (Heidelberg Engineering, Inc., Heidelberg, Germany). Thickness of different retinal layers was obtained from each Posterior Pole volumetric scan. Measurements of the peripapillary RNFL thi.. View More»
DOI:
10.4172/2155-9570.1000538