ISSN: 1745-7580
+44-77-2385-9429
Elmoez Mohamed
Sudan
Research Article
Immunoinformatics Prediction of Peptide-Based Vaccine Against African
Horse Sickness Virus
Author(s): Malaz Abdelbagi, Tarteel Hassan, Mohammed Shihabeldin, Sanaa Bashir, Elkhaleel Ahmed, Elmoez Mohamed, Shawgi Hafiz, Abdah Abdelmonim, Tassneem Hamid, Shimaa Awad, Ahmed Hamdi, Khoubieb Ali and Mohammed A. HassanMalaz Abdelbagi, Tarteel Hassan, Mohammed Shihabeldin, Sanaa Bashir, Elkhaleel Ahmed, Elmoez Mohamed, Shawgi Hafiz, Abdah Abdelmonim, Tassneem Hamid, Shimaa Awad, Ahmed Hamdi, Khoubieb Ali and Mohammed A. Hassan
Background: African horse sickness (AHS) is a viral disease of equidae. It is transmitted by hematophagous Culicoides midges (Diptera, Ceratopogonidae) and causes severe disease in horse that can lead to death. African Horse Sickness Virus (AHSV) is a double-stranded RNA (dsRNA) virus with ten genome segments encoding seven structural proteins (VP1-VP7) and four non-structural proteins (NS1, NS2, NS3, NS3A). The aim of this study is to analyze (VP2) protein of the African Horse Sickness Virus (AHSV) strains reported in the National Center for Biotechnology Information database (NCBI) database to select all possible epitopes that can be used to design a peptide vaccine.
Materials and methods: A total of 27 outer capsid protein (VP2) sequences of African Horse Sickness Virus (AHSV) were retrieved from the National Center for Biotechnology Info.. View More»
DOI:
10.4172/1745-7580.1000135