Medicinal & Aromatic Plants

Medicinal & Aromatic Plants
Open Access

ISSN: 2167-0412

+44 1300 500008

Elshiekh HH

Elshiekh HH

Egypt

Publications
  • Research Article
    Evaluation of Antimicrobial, Cytotoxic and Larvicidal Activity of Zygophyllum Coccineum North Sinai, Egypt
    Author(s): Elbadry MA, Elaasser MM, Elshiekh HH and Sheriff MMElbadry MA, Elaasser MM, Elshiekh HH and Sheriff MM

    The antimicrobial larvicidal and cytotoxic properties of Zygophillum coccinium collected from desert of north Sinai, Egypt. Antimicrobial activity of Z. coccinium extracts showed that ethyl acetate extract was the most potent antimicrobial effect on bacterial and fungal test organisms against P. aeruginosa with inhibition zone 20 mm and F. moniliforme with inhibition zone 22 mm. Cytotoxic effect of Z. coccinium extracts indicated that acetone extract showed maximum cytotoxic activity on HeLa cell line, whereas methanol extract showed maximum cytotoxic activity on MCF-7 cell line with cell line viability 13.36 and 35.19%, whereas the results of IC50 in HeLa cell line showed that the boiled water ethyl acetate extract had the most potent IC50 with 6.25 µg/ml. the results of IC50 in MCF-7 cell line the petroleum ether extract had the most potent IC50 with 18.75 µg/ml. Ethyl acetate.. View More»
    DOI: 10.4172/2167-0412.1000214

    Abstract PDF

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