ISSN: 2576-1447
+44 1478 350008
Elsisy MK
Faculty of Science,
Egypt
Research Article
The Antitumor Potential of Quercetin on Solid Ehrlich Tumor in Female Mice
Author(s): Elsisy MK *, Ibrahim WM, Salama AF and Kasem SM
Elsisy MK *, Ibrahim WM, Salama AF and Kasem SM
Background: The unusual accelerated division of group of cells is known as tumor, which may spread out through the body causing what is known as cancer. Quercetin is a well-known flavonoid which is abundant in many plants, and thought to have many therapeutic effects.
Aim of the study: The study performed to evaluate the anti-tumor potential of Quercetin against solid Ehrlich tumor in female mice.
Method: The study was carried out on 5 groups of female mice; Group I (Negative control), group II (Ehrlich tumor only), group III (Ehrlich+Methotrexate), group IV (Ehrlich+Quercetin) and group V (Ehrlich+Methotrexate +Quercetin). Estimation of Quinone Reductase and Aromatase enzymes activities, Malondialdehyde(MDA) concentration, Tumor Volume, percentage of DNA damage and Survivability were detected, in addition to genom.. View More»