ISSN: 2161-1149 (Printed)
+44-77-2385-9429
Ercan Kaydok
Physical Medicine and Rehabilitation,
Niğde
Turkey
Case Report
Thrombocytosis Development due to the Use of Methotrexate in a Patient with Rheumatoid Arthritis
Author(s): Ercan Kaydok and Ender Salbas
Ercan Kaydok and Ender Salbas
Rheumatoid arthritis is a systemic rheumatic disease that affects various organs and systems. In the course of rheumatoid arthritis, various blood disorders including thrombocytosis (>400.000/mm3), an increase in the platelet count are observed. Methotrexate is a disease-modifying agent used in the treatment of Rheumatoid Arthritis and various rheumatic diseases. During methotrexate treatment, hematologic problems such as leukopenia, anemia, and thrombocytopenia are observed generally due to bone marrow suppression. In our case report, we aimed to present a 56 year-old patient who has arthritis of both hands and was diagnosed with rheumatoid arthritis and whose platelet values were initially within normal limits and then increased up to the level of 808.000/microliter despite a clinical and laboratory suppression in the disease activity after the initiation of methotrexate treatmen.. View More»
DOI:
10.4172/2161-1149.1000236