ISSN: 2155-9554
+44 1478 350008
Erdinç Serin
Turkey
Research Article
Cellular Immune Response in Patients with Chronic Plaque Type Psoriasis: Evaluation of Serum Neopterin, Procalcitonin, Anti-Streptolysin O and C Reactive Protein Levels
Author(s): Yaşar Ibrahimbaş, Mualla Polat, Erdinç Serin and Ali Haydar ParlakYaşar Ibrahimbaş, Mualla Polat, Erdinç Serin and Ali Haydar Parlak
Background: Psoriasis is characterized by T-cell mediated hyperproliferation of keratinocytes initiated by antigen presenting cells on the skin. Environmental factors including β hemolytic streptococcus infections and multiple genetic components may be responsible for the pathogenesis of the disease. However the antigen which initiates the immunologic reactions has not yet been known. We aimed to evaluate the relationship between streptococcal as well as other bacterial infections and psoriasis via measurement of some infection markers.
Materials and methods: The study included 40 patients with exacerbations of chronic plaque type psoriasis lesions and 40 healthy individuals. Disease activity in study group was determined according to the score of psoriasis area and severity index. Antistreptolysin O, C-reactive protein, procalcitonin and .. View More»
DOI:
10.4172/2155-9554.1000107