Journal of Clinical & Experimental Dermatology Research
Open Access

Eric C. Vonderheid

Publications

• Research Article
  Prognostic Implications of Blood B Ratings for Erythrodermic Cutaneous T cell Lymphoma
  Author(s): Eric C. Vonderheid Eric C. Vonderheid
  
  Objective: The magnitude of blood involvement in cutaneous T cell lymphoma (CTCL) has prognostic significance. Several groups have proposed hematologic criteria for B ratings for use in clinical staging of CTCL, but in practice B ratings are only relevant for the staging of erythrodermic CTCL without lymph node or visceral involvement, i.e., T4N0-2M0B0 defines sub-stage IIIA, T4N0-2M0B1 defines sub-stage IIIB and T4N0-2M0B2 defines sub-stage IVA1. This retrospective study examines the effect of various B rating criteria on prognoses of patients with erythrodermic CTCL. Methods: At initial presentation, 152 patients diagnosed with E-CTCL had quantitative Sézary cell counts performed on blood smears and CD4+/CD8- ratios determined in the blood by flow cytometry. In addition, 39 patients had percentages of CD4+CD26- and CD4+CD7- lymphocy.. View More»
  DOI: 10.4172/2155-9554.1000452

  Abstract PDF

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