Journal of Cell Science & Therapy
Open Access

Ewelina Augustyniak

Publications

• Review Article
  Induced Pluripotent and Mesenchymal Stem Cells as a Promising Tool for Articular Cartilage Regeneration
  Author(s): Tomasz Trzeciak, Ewelina Augustyniak, Magdalena Richter, Jacek Kaczmarczyk and Wiktoria SuchorskaTomasz Trzeciak, Ewelina Augustyniak, Magdalena Richter, Jacek Kaczmarczyk and Wiktoria Suchorska
  
  The application of stem cells in regenerative medicine has recently become a rapidly growing field, holding promise for combating a number of orthopedic disorders including osteodegenerative ones (osteoporosis and osteoarthritis). Although the differentiation of stem cells into chondrocytes is now intensively investigated on a laboratory scale, implementing the laboratory protocols in clinical practice requires a scale-up culture. In order to apply this technique many aspects of stem cell bioprocessing such as optimal culture conditions for anchoragedependent or anchorage-independent cells and the type of culture must be taken into account. The presence of microcarriers and/or scaffolds for adherent cells is essential, since they provide a three-dimensional microenvironment indispensable for cell growth. For treatment of osteoarthritis, induced pluripotent stem cells and mesenchymal s.. View More»
  DOI: 10.4172/2157-7013.1000172

  Abstract PDF

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