Journal of Clinical and Experimental Ophthalmology

Journal of Clinical and Experimental Ophthalmology
Open Access

ISSN: 2155-9570

Fabiano Montiani-Ferreira

Publications
  • Research Article
    Clinical and Histologic Comparison of Conjunctival Changes Induced by Antiglaucoma Beta Blockers, Carbonic Anhydrase Inhibitors, Alfa Agonists and Fixed Combinations with and without Preservatives
    Author(s): Heloisa Helena Russ, Amalia Turner-Gianicco, Fabiano Montiani-Ferreira and Leandro Lima Heloisa Helena Russ, Amalia Turner-Gianicco, Fabiano Montiani-Ferreira and Leandro Lima

    Background: The objective of this research was to evaluate and compare clinical tests, histological and immunohistochemical changes induced by antiglaucoma beta blockers, carbonic anhydrase inhibitors, alfa agonists and fixed combinations containing benzalkonium chloride (BAK) and without preservative (BAKFREE) in the conjunctiva of rabbits. A total of 60 rabbits (120 eyes), were divided into six groups, and treated during 30 days with: dorzolamide 2%+timolol maleate 0.5% BAK, dorzolamide 2%+timolol maleate 0.5%BAKFREE, brinzolamide 1% +timolol maleate 0.5% BAK, brimonidine 0.2%+timolol maleate 0.5%BAK, timolol maleate 0.5%BAK and control solution BAK. Right eyes served as controls and received no medication. Corneal touch threshold (CTT), Schirmer tear test (STT) and intraocular pressure (IOP) were measured during pre and post treatme.. View More»
    DOI: 10.4172/2155-9570.1000606

    Abstract PDF

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