Chemotherapy: Open Access
Open Access
ISSN: 2167-7700
ISSN: 2167-7700
Faiz Anwer
Tanzania
Research Article
Prognostic Role of Microvascular Density and Mucin Production in 56 Cases of
Adenocarcinoma of Lung- An Experience from a Center in Lahore, Pakistan
Author(s): Ehsan Ullah, Abdul Hannan Nagi, Muhammad Ashraf, Ahmed Khurshid Pasha, Keri Renee Maher and Faiz Anwer
Ehsan Ullah, Abdul Hannan Nagi, Muhammad Ashraf, Ahmed Khurshid Pasha, Keri Renee Maher and Faiz Anwer
Introduction: The relative incidence of adenocarcinoma of the lung is increasing, and it is now the most common primary lung malignancy. This study examines certain clinical and pathological factors which may affect patient survival in lung adenocarcinoma in the developing country of Pakistan. Methods: This is a descriptive study involving 56 patients with biopsy-proven primary adenocarcinoma of lung. Biopsy tissues were reviewed along with medical record case histories. Formalin-fixed, paraffin-embedded tissue specimens were used for mucin histochemistry with mucicarmine, periodic acid Schiff (PAS) and alcian blue stains. Immunohistochemistry (IHC) with monoclonal antibodies against CD34 was used for assessment of microvascular density. Mast cell density was measured on Toluidine blue stained sections. Results: Mean age of patients was 55.96 ± 1.67 years. Male to female ratio .. View More»
DOI:
10.4172/2167-7700.1000194