Clinical & Experimental Cardiology
Open Access

Fanggang Cai

Publications

• Research Article
  Pathologic changes of pancreatic endothelial cells in Diabetic Rat
  Author(s): Jie Wu, Xiaorong Wang, Shao Dan Feng, Quwen Li and Fanggang Cai Jie Wu, Xiaorong Wang, Shao Dan Feng, Quwen Li and Fanggang Cai
  
  Aim: The study is to explore the relationship between pancreas endothelial cell injury and diabetes. Methods: To induce with a single intraperitoneal injection of streptozotocin (STZ) for diabetic animal models, and collected the blood after 8 weeks, the level of Angiogenin-1 (Ang-1) and its receptor (Tie-2), vascular cell adhesion molecule-1 (VCAM-1) were determinated by ELISA method, histopathological examination of the pancreas, and observed pathological conditions of the pancreas endothelial cell injury in the models. Results: The results showed that the level of ang-1, tie-2 and VCAM-1 were 585.04 ± 45.32 (pg/ml), 2399.40 ± 124.85 (pg/ml), 117.69 ± 12.34 (μg/L) in the Diabetes groups which were higher than that in control groups 551.29 ± 31.86 (pg/ml), 2103.27 ± 152.89 (pg/ml) a.. View More»
  DOI: 10.4172/2155-9880.1000552

  Abstract PDF

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