Journal of Depression and Anxiety
Open Access

Felix Schlachetzki

Publications

• Research Article
  Influence of Positive End-Expiratory Pressure Ventilation on Cerebral Perfusion and Cardiac Hemodynamics
  Author(s): Roland Backhaus, Elisabeth Torka, Michael Ertl, Lukas Kirzinger, Andrea Wagner, Dobri Baldaranov, Felix Schlachetzki and Kornelius Fuchs Roland Backhaus, Elisabeth Torka, Michael Ertl, Lukas Kirzinger, Andrea Wagner, Dobri Baldaranov, Felix Schlachetzki and Kornelius Fuchs
  
  Objective: Positive end-expiratory pressure (PEEP) ventilation is used to prevent alveolar collapse and improve oxygenation. PEEP ventilation hinders venous backflow to the right atrium as well as venous outflow from the brain including the spinal cord. This may have an effect on cardiac output (CO) and could result in an elevation in intracranial pressure (ICP) — an important cause of secondary brain injury. The aim of this study was to investigate the effect of moderate changes in PEEP values on hemodynamics and cerebral perfusion in neurological patients experiencing respiratory failure. Methods: The study focused on 7 patients in a neurological intensive care unit who suffered from respiratory failure. Cerebral blood flow velocity was measured using transcranial color-coded duplex sonography (TCCS) while moderate changes in PEEP le.. View More»
  DOI: 10.4172/2167-1044.1000285

  Abstract PDF

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