ISSN: 2167-0277
+44 1478 350008
Ferdinand Zizi
Tanzania
Review Article
Sleep Disorders in Postmenopausal Women
Author(s): Shazia Jehan, Alina Masters-Isarilov, Idoko Salifu, Ferdinand Zizi, Girardin Jean-Louis, Seithikurippu R Pandi-Perumal, Ravi Gupta, Amnon Brzezinski and Samy I McFarlane
Shazia Jehan, Alina Masters-Isarilov, Idoko Salifu, Ferdinand Zizi, Girardin Jean-Louis, Seithikurippu R Pandi-Perumal, Ravi Gupta, Amnon Brzezinski and Samy I McFarlane
One of the core symptoms of the menopausal transition is sleep disturbance. Peri-menopausal women often complain of difficulties initiating and/or maintaining sleep with frequent nocturnal and early morning awakenings. Factors that may play a role in this type of insomnia include vasomotor symptoms, changing reproductive hormone levels, circadian rhythm abnormalities, mood disorders, coexistent medical conditions, and lifestyle. Other common sleep problems in this age group, such as obstructive sleep apnea and restless leg syndrome, can also worsen the sleep quality. Exogenous melatonin use reportedly induces drowsiness and sleep and may ameliorate sleep disturbances, including the nocturnal awakenings associated with old age and the menopausal transition. Recently, more potent melatonin analogs (selective melatonin-1 (MT1) and melatonin-2 (MT2) receptor agonists) with prolonged effec.. View More»
DOI:
10.4172/2167-0277.1000212