Clinical Pediatrics: Open Access
Open Access

Filip Rubić

Publications

• Research Article
  Association of Asthma Symptoms and Exacerbation with Inflammatory Biomarkers
  Author(s): Marta Navratil, Irena Ivkovic Jurekovic, Iva Topalusic, Alen Svigir, Natasa Andrijasevic and Filip RubicMarta Navratil, Irena Ivkovic Jurekovic, Iva Topalusic, Alen Svigir, Natasa Andrijasevic and Filip Rubic
  
  Objective: To investigate a relationship of asthma symptoms and exacerbations with systemic (high-sensitivity Creactive protein (hs-CRP), eosinophilic cationic protein (ECP), leukocytes) and local (exhaled NO (FENO), pH and urates in exhaled breath condensate (EBC) and exhaled breath temperature (EBT)) inflammatory biomarkers (BMs) in asthmatic children. Methods: This cross-sectional study comprised 93 consecutive asthmatic patients (age 6-18 years, 22 girls) with mild intermittent asthma ((IA), N=44) and mild to moderate persistent asthma ((PA), N=49). Medical history (asthma symptoms and exacerbation), pulmonary function, FENO, EBT, samples of exhaled breath and peripheral blood were collected. Results: Local BMs (EBC urates and EBT) showed stronger correlation with asthma symptoms then systemic BMs (hs-CRP, blood co.. View More»
  DOI: 10.4172/2572-0775.1000122

  Abstract PDF

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