Journal of Women's Health Care
Open Access
ISSN: 2167-0420
ISSN: 2167-0420
Francis Olayemi Adebayo
University of Abuja Teaching Hospital,
Abuja-FCT
Nigeria
Research Article
A Comparison of 25 μg with 50 μg Misoprostol for Cervical Ripening and
Induction of Labor
Author(s): Francis Olayemi Adebayo, Olatunde Onafowokan and Nathaniel AdewoleFrancis Olayemi Adebayo, Olatunde Onafowokan and Nathaniel Adewole
Background: Misoprostol is increasingly being accepted as a standard agent for cervical ripening and induction of labor. The lowest effective dose is still not known. Materials and Methods: This was an open label clinical trial of one hundred and eighty four women with obstetrics or medical indications for induction of labor at University of Abuja Teaching Hospital, Abuja. Women were grouped to receive either 25 μg or 50 μg of intravaginal misoprostol. The main outcome measure was inductionvaginal delivery interval while the secondary outcome measures were requirements for oxytocin augmentation, mode of delivery, frequency of tachsystole/hyperstimulation, as well as feto-maternal outcomes. Data was analyzed using SPSS version 21.0. Chi-square test was used to compare categorical variables. Mann-Whitney test was used to analyze continuous variables of the two treatment groups. P.. View More»
DOI:
10.4172/2167-0420.1000378