Journal of Clinical and Experimental Ophthalmology
Open Access

Francisco Javier Carreras

Publications

• Review Article
  Glaucoma as a Tax on Hominid Evolution. Constraints of the Experimental Animal Models of Glaucoma
  Author(s): Francisco Javier Carreras Francisco Javier Carreras
  
  Glaucoma continues to be a mysterious disease. High intraocular pressure (IOP), once the landmark of the disease, has been relegated to the humble role of risk factor, despite the fact that lowering IOP continues to be the only partially successful treatment. Even with an IOP successfully controlled to statistical standards, many patients still mysteriously continue to progressively lose neural tissue. A novel pathogenetical mechanism has recently been put forward as the main agent of the disease. In this new light, some structural details of the human eye, the result of the peculiar evolutionary development, take on an unexpected role in the presentation of the disease. As results of cladistics analysis, the human eye appears as particularly prone to suffering glaucoma as a consequence of the evolutionary path taken. That makes glaucoma essentially a human (and related hominid) scour.. View More»
  DOI: 10.4172/2155-9570.1000527

  Abstract PDF

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