Journal of Drug Metabolism & Toxicology
Open Access

Fumihiro Ozawa

Publications

• Research Article
  Ten-week Whole-body Inhalation Toxicity Study of Chlorine Dioxide Gas in Rats
  Author(s): Norio Ogata, Tomoko Koizumi and Fumihiro Ozawa Norio Ogata, Tomoko Koizumi and Fumihiro Ozawa
  
  Chlorine dioxide (ClO2) gas can protect against influenza virus infection at a concentration of 0.03 parts par million (volume/volume), which is believed to be nontoxic in humans. This suggests an opportunity for the development of a novel protective method against airborne infectious diseases. This method is especially applicable to the highly pathogenic H5N1 influenza virus, as there is currently no safe and effective protection against H5N1. However, concerns remain regarding the safety of ClO2 gas for protection against virus infection, especially whether a concentration of 0.03 parts per million is really non-toxic when it is used for humans in closed or semiclosed spaces. In view of the importance of the usefulness and necessity of low concentration ClO2 gas treatment, it is critical to determine the ?no observed adverse effect level? (NOAEL) of ClO2 gas. In 1972 Paulet and Desbrou.. View More»
  DOI: 10.4172/2157-7609.1000143

  Abstract PDF

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