ISSN: 2329-9509
+44 1478 350008
Gabriel Fernandes
Tanzania
Research Article
Fish Oil with Higher DHA Content and Voluntary Exercise Decreases Postmenopausal Bone Loss
Author(s): Jameela Banu, Gabriel FernandesJameela Banu, Gabriel Fernandes
There is increasing evidence suggesting that fish oil (FO) decreases bone resorption by reducing osteoclastogenesis and regular exercise (EX) increases bone mass. EX is associated with increasing bone formation. Therefore, the combined effects of FO intake and EX may have additive effects by both increasing bone formation and decreasing bone resorption. To demonstrate this, we studied the effects of FO and EX on the bone of mice after an ovariectomyinduced bone loss.
Twelve months old C57BL/6 female mice were either sham operated or ovariectomized, divided into different dietary and EX group and maintained for 3 months before sacrifice.
The distal femoral metaphysis (DFM) showed significantly higher total BMC in both the FO sham sedentary groups. 30/20 ovariectomized sedentary mice had higher total bone mineral content (BMC). EX significantly increased BMC in the contr.. View More»
DOI:
10.4172/2329-9509.1000188