Journal of Developing Drugs
Open Access
ISSN: 2329-6631
+44 1478 350008
ISSN: 2329-6631
+44 1478 350008
Gathumbi K Peter
Kenya
Research Article
In Vivo Anti-diabetic Effects of Aqueous Leaf Extracts of Rhoicissus tridentata in Alloxan Induced Diabetic Mice
Author(s): Mwangi J Mukundi, Njagi E N Mwaniki, Ngugi M Piero, Njagi J Murugi, Agyirifo S Daniel, Gathumbi K Peter and Muchugi N AliceMwangi J Mukundi, Njagi E N Mwaniki, Ngugi M Piero, Njagi J Murugi, Agyirifo S Daniel, Gathumbi K Peter and Muchugi N Alice
The drawbacks associated with conventional anti-diabetic agents have largely stimulated desire for alternative and
complementary anti-diabetic agents, majority of which are plant-derived. The medicinal plant, Rhoicissus tridentata has
been used extensively in traditional medical practice against various ailments. However, its ethno medicinal use against
diabetes mellitus has not been scientifically evaluated and validated. This study was, therefore, designed to evaluate
the anti-diabetic potential of aqueous leaf extracts of Rhoicissus tridentata in alloxan induced diabetic mice. As the
results show, the aqueous leaf extracts of Rhoicissus tridentata showed anti-diabetic activity. The intraperitoneal route
of herbal extract administration was found to be more effective than the oral route. Further, qualitative and quantitative
phytochemical screening of aqueous leaf extracts of Rh.. View More»
DOI:
10.4172/2329-6631.1000131