Journal of Thyroid Disorders & Therapy
Open Access

GD Valk

Publications

• Research Article
  High Negative Predictive Value (NPV) Of Undetectable TSH Stimulated Tg For Disease Recurrence In Both Low And High Risk Differentiated Thyroid Cancer
  Author(s):  SGA de Meer, MR Vriens1, GD Valk, IHM Borel Rinkes and B de Keizer  SGA de Meer, MR Vriens1, GD Valk, IHM Borel Rinkes and B de Keizer
  
  The extend, intensity and timing of the follow-up of differentiated thyroid cancer (DTC) patients remains unclear. Recent studies identified an undetectable TSH stimulated Tg measurement after one year as a prognostic factor for the risk of recurrence during further follow-up, thereby further dividing patients based on risk for recurrence. Because patients experience their disease on an emotional basis rather than related to actual disease severity, follow-up should be targeted to detect recurrence without ‘over-investigating’ patients. The aim of our study was to investigate the recurrence rate in high and low risk patients with DTC and the need for repeated (TSH stimulated) Tg measurement. Methods: We retrospectively reviewed the medical records of 264 DTC patients with absent Tg-Ab and identified the patients with persistent/ recurrent disease. We compared recurrence ra.. View More»
  DOI: 10.4172/2167-7948.1000149

  Abstract PDF

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