Journal of Clinical and Cellular Immunology
Open Access

Geethalakshmi S

Publications

• Research Article
  Inclusion of Seromarkers to Exclude Hepatitis B Virus Infection via Transfusion in Voluntary Blood Donors
  Author(s): Pushkala S, Geethalakshmi S and Gurunathan KS Pushkala S, Geethalakshmi S and Gurunathan KS
  
  Introduction: Hepatitis B Virus (HBV) infection is a serious viral infection causes acute and chronic hepatitis. Transfusion of blood and blood products is the predominant route of transmission of HBV. As per NACO guidelines, in India, donor blood is screened for HBsAg, anti-HCV antibodies, anti-HIV antibodies; slide/card rapid screening for malarial parasites and VDRL for Syphilis. Blood banks in India are only equipped to carry out rapid card test or ELISA for routine screening of HBV, HCV and HIV infections. In developed countries use Nucleic Acid Testing (NAT) were in place for screening and diagnosis of viral infections during window period. NAT assays are highly sensitive, specific and robust but require skilled manpower and specialized infrastructure and thus may not be cost-effective. Objectives: To explore the current sero-preva.. View More»
  DOI: 10.4172/2155-9899.1000550

  Abstract PDF

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