Journal of Clinical Chemistry and Laboratory Medicine

Journal of Clinical Chemistry and Laboratory Medicine
Open Access

ISSN: 2736-6588

Genet Ashebir

Genet Ashebir

Ethiopia

Publications
  • Research Article
    Application of Cancer Antigen 125 Test in Diagnosis of Pulmonary Tuberculosis
    Author(s): Bikila Nagasa, Atsbeha Gebreegziabxier, Feyissa Challa, Meron Silashi, Zeleke Geto, Tigist Getahun, Genet Ashebir, Abenezer Ayalkebet, Tadesse Lejisa, Yosef Tolcha, Demiraw Bikila, Wossene Habtu and Desta Kassa Bikila Nagasa, Atsbeha Gebreegziabxier, Feyissa Challa, Meron Silashi, Zeleke Geto, Tigist Getahun, Genet Ashebir, Abenezer Ayalkebet, Tadesse Lejisa, Yosef Tolcha, Demiraw Bikila, Wossene Habtu and Desta Kassa

    Objective: Cancer antigen125 (CA-125) test is the most frequently used biomarker for ovarian cancer, but according to some literatures CA125 test can discriminate active pulmonary tuberculosis from inactive cases in tuberculosis (TB) patients. Therefore the objective of this work was to further study application of CA-125 test in identification of active tuberculosis from inactive cases and for evaluation of response to anti-TB treatment. Methods: Plasma CA125 of 30 patients with active tuberculosis cases (group 1), 19 cases with inactive tuberculosis (group 2) and 28 healthy subjects (group 3) was measured and compared. Measurement of CA-125 was done only once in group 2 and 3 but it was repeated in group 1 at two and six month of anti-TB treatment. Independent t-test was used to compare CA125 level between groups and paired t-test was used to.. View More»

    Abstract PDF

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