Medicinal & Aromatic Plants
Open Access

George O Orinda

Publications

• Research Article
  In-Vivo Oral and Intraperitoneal Administration of Extract from Vernonia lasiopus
  Author(s): Njeri L Kimani, Eliud NM Njagi and George O Orinda Njeri L Kimani, Eliud NM Njagi and George O Orinda
  
  Diabetes mellitus in Kenya is a major health concern as it is known to result in mobility, mortality, and long-term complications. Conventional drugs used in the management of diabetes mellitus are unavailable, expensive, and have numerous side effects. Vernonia lasiopus plant has a folkloric usage in diabetes mellitus management though its efficacy needs to be evaluated scientifically. This study therefore aimed at establishing in vivo antihyperglycemic effect of aqueous leaf extract from Vernonia lasiopus in alloxan-induced diabetic male albino mice. Eight groups of mice each group having five mice were used in the study. The plasma sugar lowering effect was monitored after intraperitoneal and oral administration of Vernonia lasiopus extract at doses of 25, 48.4, 93.5, 180.9 and 350 mg/kg body weight. The treatment effects of extracts were compare.. View More»
  DOI: 10.4172/2167-0412.1000308

  Abstract PDF

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