Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
+44 1300 500008
ISSN: 2167-7948
+44 1300 500008
Geurs F
Reg Zh Sint Maria,
Ziekenhuislaan 100, Halle, Vl Brabant, 1500
Belgium
Case Report
Remarkable Effect of Metronomic Chemotherapy in Diffuse Lung Metastases of Thyroid Cancer
Author(s): Criel M and Geurs F
Criel M and Geurs F
We present a patient with respiratory insufficiency due to progressive lung metastases of thyroid cancer. Low dose i.v. vinblastin, oral cyclophosphamide and s.c. enoxaparin produced dramatic clinical improvement, a drop in thyroglobulin and prolonged disease stabilisation. This new way of giving classical chemotherapy is called metronomic chemotherapy. Its anti-angiogenic basis of activity is corroborated by the more recent drugs in thyroid cancer which share this mechanism.
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DOI:
10.4172/2167-7948.1000101