Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access

Giovanni Casafranca

Publications

• Research Article
  Sperm DNA Fragmentation is Significantly Increased in Those Men with Morphologically Abnormal Spermatozoa
  Author(s): Javier García-Ferreyra, Lucy Villegas, Rocío Romero Obst, Patricia Zavala Obst, Roly Hilario, Giovanni Casafranca, Roly Hilario, Giovanni Casafranca and Julio Dueñas-Chacón Javier García-Ferreyra, Lucy Villegas, Rocío Romero Obst, Patricia Zavala Obst, Roly Hilario, Giovanni Casafranca, Roly Hilario, Giovanni Casafranca and Julio Dueñas-Chacón
  
  Purpose: To evaluate the levels of DNA fragmentation regarding to spermatozoa morphology in male infertility patients attending Andrology Laboratory at fertility center.  Methods: Semen samples of 196 patients were analyzed using computer-assisted semen analysis (CASA). Sperm DNA fragmentation was measured by the sperm chromatin dispersion test. According to the values of sperm morphology, the groups were conformed by teratozoospermic (105 patients) and normozoospermic (91 patients) men.  Results: Subjects’ ages ranged from 21 to 68 years. Teratozoospermic men were older that the normozoospermic men (39.72 ± 7.86 vs. 36.57 ± 6.29 years; P<0.05). Values of pH were similar in both evaluated groups (P:NS). Parameters of volume, concentration, motility and vitality in teratozoospermic men were significantly lower compared .. View More»
  DOI: 10.4172/2375-4508.1000131

  Abstract PDF

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