Anesthesia & Clinical Research
Open Access

Giovanni Messina

Publications

• Research Article
  Bethametasone Prevents Plasmatic Glutamine Precipitation: An In-Vivo Study
  Author(s): Maria Caterina Pace, Maria Beatrice Passavanti, Antonio Palagiano, Fabio Arturo Iannotti, Vincenzo Pota, Antonietta Messina, Pasquale Sansone, Leonardo Pace, Pasquale Carfora, Giovanni Messina, Marcellino Monda and Caterina AurilioMaria Caterina Pace, Maria Beatrice Passavanti, Antonio Palagiano, Fabio Arturo Iannotti, Vincenzo Pota, Antonietta Messina, Pasquale Sansone, Leonardo Pace, Pasquale Carfora, Giovanni Messina, Marcellino Monda and Caterina Aurilio
  
  Glutamine (Gln) is an amino acid which plays an important regulatory role in many physiological functions and during acute or chronic human pathologies. The primary purpose of this study was to investigate potential changes of glutamine levels in the plasma of women that needed minor gynaecological surgery. The changes in glutamine levels were then evaluated in a group of patients pre-medicated with Bethametasone. In this study 46 patients were subdivided into two groups. All of them were anesthetized with loco-regional administration of mepivacaine 0.2%. Subsequently, to the first group was given placebo, whereas the second group of women was pre-medicated with Bethametasone 4 mg (i.v.). We report that in 34 patients out of 46, the minor gynaecologic surgery caused a significant decrease of glutamine (>20%) associated with an increase of postoperative pain. Interestingly, 10 out o.. View More»
  DOI: 10.4172/2155-6148.1000531

  Abstract PDF

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