ISSN: 2155-9880
+44 1300 500008
Giuseppe Allocca
Italy
Short Communication
Brugada Syndrome 26 Years Later: More Questions than Answers
Author(s): Pietro Delise, Giuseppe Allocca and Nadir SittaPietro Delise, Giuseppe Allocca and Nadir Sitta
Brugada Syndrome and Brugada type 1 ECG pattern (BrS type 1 ECG) are currently used as synonyms. However, in the vast majority of cases, BrS type 1 ECG is a benign finding, and only few patients with this pattern have a Brugada Syndrome; that is to say, they present with, or are prone to, malignant arrhythmias.
Brugada Syndrome, when defined only on the basis of the BrS type 1 ECG, has several characteristics which conflict with those of other channellopathies such as Long-QT syndrome (LQTS). For example, there is no correlation between the magnitude of ECG anomalies and prognosis, and a genetic defect is rarely recognized. In addition, patients with malignant arrhythmias in prospective and retrospective studies have different characteristics. Indeed, prospective studies have identified a number of risk factors which are useful (singly or in combination) in identifying patient.. View More»