Journal of Clinical & Experimental Dermatology Research
Open Access

Giuseppe Micali

Publications

• Research Article
  Corticosteroid Cream Once Daily plus an Emollient Cream in comparison with Corticosteroid Cream Twice Daily in Plaque Psoriasis: An Intra- Patient, Randomized Assessor-Blinded, Ultrasound Evaluation Study
  Author(s): Francesco Lacarrubba, Maria Letizia Musumeci, Massimo Milani and Giuseppe Micali Francesco Lacarrubba, Maria Letizia Musumeci, Massimo Milani and Giuseppe Micali
  
  Background: Emollients and keratolytics creams with corticosteroids have been demonstrated to be useful in plaque psoriasis (PP), improving clinical response with a steroid-sparing effect. However, so far, no trials with objective measurement evaluations are available. Aim of this intra-patient randomized, assessor-blinded, 4-week study was to evaluate, by means of ultrasound imaging, the efficacy of the combination of hydrocortisone valerate 0.1% cream (HVC) once daily with an emollient, keratolytic, keratoplastic and anti-inflammatory cream (EKC) containing urea 20%, salicylic acid 2% and niacinamide (2%) once-daily vs. HVC alone applied twice-daily in PP. Methods: Fifteen patients with mild-to-moderate PP were enrolled. For each patient two symmetrical, target lesions were selected and randomized to receive HVC+EKC or HVC alone for 4 week.. View More»
  DOI: 10.4172/2155-9554.1000243

  Abstract PDF

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