Giuseppe Petrilli (1913? – 13 May 1999?) was an Italian professor and European Commissioner. He was a non-politician appointed as the first Italian European Commissioner on the Hallstein Commission from January 1958 with responsibility for the Social Affairs portfolio. In September 1960 (or December 1960, or 8 February 1961) he resigned and was succeeded by Lionello Levi Sandri. A professor, Giuseppe Petrilli became president of IRI