Journal of Osteoporosis and Physical Activity
Open Access

Gokhan Ozgen

Publications

• Research Article
  Efficacy of Zoledronic Acid Treatment in Paget Disease of Bone
  Author(s): Emine Kartal Baykan, Sevki Cetinkalp, Gokhan Ozgen and Candeger YilmazEmine Kartal Baykan, Sevki Cetinkalp, Gokhan Ozgen and Candeger Yilmaz
  
  Purpose: Paget disease is a disease of bone of unknown etiology with increased bone turnover that results in defective bone microarchitecture and bone deformity. Bisphosphonates are used in symptomatic Paget disease of bone. Clinical trials have shown that zoledronic acid was more effective than other bisphosphonates in treatment of Paget disease. Methods: In this study, we retrospectively reviewed the remission and relapse statuses of 12 patients with Paget disease of bone, who were seen as outpatients between October 2011 and October 2013. We evaluated alkaline phosphates, osteocalcin, deoxypyridinoline levels measured before and at 6th, 12th, 18th months of treatment. Results: Pretreatment values for alkaline phosphates, deoxypyridinoline, osteocalcin were as follows; 473 ± 256 .. View More»
  DOI: 10.4172/2329-9509.1000120

  Abstract PDF

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