Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Golnar Mohamed Fathy
Egypt
Research Article
Ketofol for Procedural Sedation and Analgesia in Children with Acute
Lymphoblastic Leukemia
Author(s): Ahmed Ahmed Ibrahim Ahmed, Golnar Mohamed Fathy, Mostafa Galal Mostafa and Mohamed AM Mostafa
Ahmed Ahmed Ibrahim Ahmed, Golnar Mohamed Fathy, Mostafa Galal Mostafa and Mohamed AM Mostafa
Objectives: The aim of this work is to study the effects, adverse effects and recovery time of IV mixed propofol and ketamine (ketofol) in 3:1 ratio as a sedative analgesic in children with acute lymphoblastic leukemia undergoing bone marrow aspiration.
Methods: This was a prospective, observational pilot study of twenty patients; 3-12 years with ALL requiring sedation for BMA were included. Mixture of ketofol (3:1) was administered intravenously in a dose of 0.5 mg⁄kg at 30-second to 1-minute intervals aiming to achieve a sedation level of 3 or 4 on Ramsay scale to start the procedure. Patient satisfaction was the primary outcome in our study. Faces pain scale-revised (FPS-R) was used to assess the degree of analgesia. Secondary outcomes included sedation time, recovery time, adverse events and safety.
Results: .. View More»
DOI:
10.4172/2155-6148.1000515