Endocrinology & Metabolic Syndrome
Open Access

Gregory C. Gass

Publications

• Review Article
  Rapid Communication - Effect of Exercise Training on Asymmetric Dimethylarginine Concentration in Women Aged 65-74 years with Type 2 Diabetes
  Author(s): Kevin R Serre, Michael J Simmonds, Surendran Sabapathy, Clare L Minahan and Gregory C GassKevin R Serre, Michael J Simmonds, Surendran Sabapathy, Clare L Minahan and Gregory C Gass
  
  Aims/hypothesis: Basal plasma concentration of asymmetric dimethylarginine (ADMA), an endogenous, competitive inhibitor of nitric oxide synthase, is elevated in patients with type 2 diabetes. ADMA may contribute to the endothelial dysfunction and associated vascular complications observed in individuals with type 2 diabetes. The present study investigated the effect of 12 weeks of supervised walking exercise on plasma ADMA concentration in women aged 65-74 years with type 2 diabetes. Materials and methods: Fourteen women (aged 69 ± 3 yrs) with uncomplicated type 2 diabetes, completed 12 weeks of supervised, moderate-intensity walking at an intensity equivalent to their individual gas-exchange threshold. Blood was sampled for ADMA concentration before and after a 6-week intervention-free control period, and again after 6 and 12 weeks of exercise training. Results: Plasma ADMA conc.. View More»
  DOI: 10.4172/2161-1017.S5-001

  Abstract PDF

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