Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Guangjie Chen
Shanghai JiaoTong University School of Medicine, Shanghai Institute of Immunology,
Shanghai 200025
China
Review Article
IL-21 and Related Diseases
Author(s): Xiaoyin Niu and Guangjie ChenXiaoyin Niu and Guangjie Chen
IL-21, which is produced by activated NKT cells and CD4+ T cells, exhibits pleiotropic effects not only on a variety of immune cells but also on non-immune cells. It has been demonstrated that IL-21 plays significant roles in the process of autoimmune diseases, inflammatory diseases and cancers. This review intends to give the reader an overview of this cytokine and the relationships between IL-21 and the related diseases of different body systems... View More»
DOI:
10.4172/2155-9899.S1-008