ISSN: 2167-7948
+44 1300 500008
Guda BB
Kyiv 04114
Ukraine
Dr. Bogdan B. Guda is a distinguished medical doctor and Ph.D. holder specializing in endocrine surgery at the V.P. Komisarenko Institute of Endocrinology and Metabolism, part of the National Academy of Medical Sciences of Ukraine in Kyiv. As a senior researcher in the Department of Surgery, Dr. Guda focuses on the diagnosis and treatment of thyroid malignancies, contributing significantly to the field through both clinical practice and scholarly research. In 2015, Dr. Guda co-authored a pivotal study titled "The Expression and Activation of Extracellular Signal-Regulated Kinase-1/2 and Proliferating Cell Nuclear Antigen Content in Normal Tissue and Human Thyroid Tumors," published in the SM Journal of Endocrinology and Metabolism. This research investigated the roles of ERK1/2 and PCNA in thyroid tumors, providing insights into their potential as diagnostic and prognostic markers. Furthering his contributions to thyroid cancer research, Dr. Guda authored a 2019 study titled "Survival of Patients with Thyroid Papillary and Follicular Carcinoma: Similarity and Difference of Prognostic Factors," published in ScienceRise: Medical Science. This cohort retrospective study analyzed various prognostic factors affecting patient survival, offering valuable data to inform treatment strategies. In 2020, Dr. Guda co-authored "Activation of the PI3K/AKT/MTOR/p70S6K1 Signaling Cascade in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes," featured in the Ukrainian Biochemical Journal. This study explored the activation state of specific signaling pathways in immune cells of diabetic patients, contributing to the understanding of molecular mechanisms involved in type 2 diabetes. Dr. Guda's dedication to advancing endocrine surgery and endocrinology is evident through his extensive research and clinical practice. His work continues to enhance the medical community's understanding of complex endocrine disorders, ultimately improving patient care and outcomes.
Research Article
Main Prognostic Factors for Well Differentiated Thyroid Cancer: Analis of Combined Patients Treatment Results during 20 Years after Surgery
Author(s): Guda BB, Kovalenko AE, Bolgov MY, Taraschenko YM and Mykhailenko NIGuda BB, Kovalenko AE, Bolgov MY, Taraschenko YM and Mykhailenko NI
Background: In general, the prognosis in patients with well differentiated thyroid carcinoma (WDTC) is excellent. However, there are small cohorts of patients who experience a more aggressive form of disease which is often associated with certain poor prognostic factors. Identifying these patients at an early stage is imperative for guiding treatment decisions. The purpose of the work is to study the cumulative survival of patients with WDTC, depending on a number of clinical and biological characteristics of tumors.
Methods: A retrospective cohort study of patients operated on WDTC in the period from 1995 to 2015 (5526 people). Each patient was analyzed according to age, gender, tumor size and characteristics of the TNM (7 editions), clinical stage, volume of surgery, number of points on the MACIS scale, risk group, number of courses of rad.. View More»
DOI:
10.4172/2167-7948.1000228