Journal of Thyroid Disorders & Therapy
Open Access

Guilherme Souza Silva

Publications

• Research Article
  Cervical Lymph Node Dissection in Papillary Thyroid Cancer: Pattern and Predictive Factors of Regional Lymph Node Metastas
  Author(s): Guilherme Souza Silva, Paulo Roberto Savassi Rocha, Jose Maria Porcaro Salles, Gustavo Meyer Moraes and Alexandre Andrade Sousa Guilherme Souza Silva, Paulo Roberto Savassi Rocha, Jose Maria Porcaro Salles, Gustavo Meyer Moraes and Alexandre Andrade Sousa
  
  Background: Papillary thyroid carcinoma (PTC) exhibits a high index of cervical lymphatic dissemination. Methods: Retrospective study of 101 cases of PTC subjected to total thyroidectomy associated with cervical lymph node dissection. Results: The incidence of neck metastasis was 50.5%, and all the metastases wereipsilateral to the primary tumor. Although the participants with metastases (N+) hadmore dissected lymph nodes than the group without metastases (p = 0.01), the lymphnode size was not a determinant of malignancy (p=0.34). Uni and multivariate analyses showed tumor size ≥ 1.0 cm, angiolymphatic invasion, and multicentric diseases were associated with lymphatic dissemination (p < 0.05). Conclusions: Factors predictive of cervical lymph node metastasis were tumor size ≥ 1.0cm, multicentric disease and angiolymphatic invasion. All the metastases wereipsilateral to the pr.. View More»
  DOI: 10.4172/2167-7948.1000150

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