Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Gulab Chandra
India
Research Article
Ameliorative Effect of Zinc Supplementation to Lead Exposed Goat Kids on Immune Status
Author(s): Muneendra Kumar, Harjit Kaur, Bhupendra T. Phondba, Veena Mani, Gulab Chandra and Rijusmita Sarma DekaMuneendra Kumar, Harjit Kaur, Bhupendra T. Phondba, Veena Mani, Gulab Chandra and Rijusmita Sarma Deka
In vivo studies were conducted to observe the adverse effects of lead and protective effect of zinc on lymphocyte proliferation and total immunoglobulins concentration in eighteen crossbred (Alpine x Beetal) male goat kids (around 6 months of age). They were divided into three groups i.e. Group I (Control), Group II (Control + 50 ppm Pb) and Group III (Control + 50 ppm Pb + 50 ppm Zn). All the kids were fed as per standard dietary requirements for a period of 90 days. Blood samples were collected on 0, 30, 60 and 90 days of Pb and Zn supplementation for lymphocyte separation and total immunoglobulin. A fixed no. of cells (2x106) was grown in culture for 72 hours for studying the lymphocyte proliferation. Overall average lymphocyte proliferation response at the end of 90 days duration was significantly (P < 0.05) lower in Pb supplemented group II (1.088) as compa.. View More»
DOI:
10.4172/2155-9899.1000119