Mycobacterial Diseases
Open Access

Gunnar Bjune

Publications

• Research Article
  Serodiagnostic Performance of Resat-6-CFP-10 in the Diagnosis of Pulmonary Tuberculosis in Ethiopia
  Author(s): Mulugeta Belay, Gunnar Bjune, Gobena Ameni, Markos Abebe and Fekadu AbebeMulugeta Belay, Gunnar Bjune, Gobena Ameni, Markos Abebe and Fekadu Abebe
  
  Background: Tuberculosis is a major public health problem globally. Lack of rapid and accurate diagnostic tests remain an obstacle for effective control. The aim of this study was to evaluate the potential of rESAT-6-CFP-10 in detecting active pulmonary tuberculosis in a high burden setting. Methodology/Principal findings: Three hundred twenty three pulmonary tuberculosis suspects were included consecutively from February 2010 to May 2010. Basic socio-demographic data as well as sputum and serum samples were collected. Of the 323 suspects, 107 were confirmed to be pulmonary tuberculosis patients using smear microscopy and culture. IgG-based ELISA was run on 204 (89 culture positive and 115 culture and smear negative) serum samples using rESAT-6-CFP-10 antigen. The sensitivity and specificity were 91.0% (83.3 % - 95.4%) and 41.7% (33.1% - 50.9%.. View More»
  DOI: 10.4172/2161-1068.1000103

  Abstract PDF

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