Andrology-Open Access
Open Access

Habib Ben Ali

Publications

• Research Article
  Effect of Seminal Transforming Growth Factorβ1 (β1) and Glutathione on Apoptosis in Spermatozoa from Tunisian Infertile Men
  Author(s): Habib Ben AliHabib Ben Ali
  
  We aimed to compare the effect of TGFB1 and glutathione on sperm necrosis in three groups of patients with increased necrospermia. The study included 120 men aged 37.6 ± 4.6 years consulting for sterility of the couple. Patients were subdivided into three groups according to the percentage of necrotic spermatozoa: necrospermia<30%; N=40), moderate necrozoospermia (50-80%, n=45) and severe necrozoospermia (>80%) For each patient, the sperm parameters were evaluated according to WHO standards, TGFB1 and glutathione Oxidized and reduced was carried out by the ELISA technique and by spectrophotometry respectively. We found a significant increase in the levels of TGFβ1 and DFI in moderate and severe necrospermia groups and positive correlations between these two factors and sperm parameters (numeration, mobility and morphology). In addition, a significant decrease in semi.. View More»
  DOI: 10.4172/2472-1212.1000172

  Abstract PDF

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