Frih Hacène is a Senior Researcher at the Laboratory of applied Neuroendocrinology, University of Annaba-Algeria, Annaba. The area of interest is biological Psychiatry (precisely neurobehaviour and neuropathology of stress). Since 1995 he began his research on the interactions between nervous system, immune system and adrenal axis, in animals (rodent, chicken, etc.) and humans. He wrote a Ph.D. (in 2007) entitled: Study of the effects of post-traumatic stress on the interaction neuro-immuno-gonadotropic humans. In 2005 (2005-2009), he participated in the program agreement Algeria-France (CMEP 05 MDU 665) in Northern Hospital Marseille (France) entitled: Study states PTSD: Epidemiological aspects, immuno-neuroendocrine and molecular levels. Currently he is responsible for a master neuro-immuno-endocrinology, project manager NRP (National Research Program) entitled: Effects of prenatal stress on the development of Toluene offspring of Wistar rats: Appearance neuro-behavioral and physiological; and provides training in the third cycle doctorate neuroscience. He has published several articles in the field of psychobiology;