Journal of Thyroid Disorders & Therapy
Open Access

Hayet Kaaroud

Publications

• Case Report
  Pulmonary Hemorrhage and Renal Involvement in Benzylthiouracil- Induced Vasculitis
  Author(s): Hayet Kaaroud, Karima Boubaker, Karima Khiari, H?di ben Maiz and Adel Kheder Hayet Kaaroud, Karima Boubaker, Karima Khiari, H?di ben Maiz and Adel Kheder
  
  Introduction: Vasculitis is a rare complication of antithyroid drugs reported with propylthiouracil, carbimazole, methimazole and Benzylthiouracil. Benzylthiouracil –induced Vasculitis are often severe forms with renal or pulmonary involvement, which can be life-threatening if left untreated .We describe the clinical course and medical management of 2 cases of severe vasculitis with alveolar hemorrhage and renal involvement occurred in 2 patients with Graves’ disease treated by Benzylthiouracil. Cases report: A 36 and 33-year-old women with Graves’ disease developed alveolar hemorrhage and acute renal failure after respectively 36 and 144 months of Benzylthiouracil therapy. Kidney biopsy showed pauci-immune crescentic glomerulonephritis in the 2 cases. Anti Neutrophil Cytoplasmic Antibody (ANCA) was positive (P- ANCA in the.. View More»
  DOI: 10.4172/2167-7948.1000114

  Abstract PDF

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