ISSN: 2155-6148
Hesham Mohamed Marouf
Faculty of Medicine,
Egypt
Research Article
Effect of Preoperative Pregabalin on Induced Hypotension and Postoperative Analgesia with Functional Endoscopic Sinus Surgery
Author(s): Hesham Mohamed Marouf, Naglaa Khalil Khalil
Hesham Mohamed Marouf, Naglaa Khalil Khalil
Background: Our target was to estimate the effect of pregabalin as premedication on deliberate hypotension and quality of the surgical site during functional endoscopic surgery for nasal sinuses (FESS) and its postoperative analgesic effect.
Materials and methods: Eighty patients ASA I-II prepared for FESS were included in this randomized research. The study encompassed 2 groups [control group (C) and pregabalin group (P)]. Patients were given either placebo capsule [group (C)] or pregabalin capsule 150 mg [group (P)] 1 h preoperatively. During surgery mean arterial blood pressure (MAP) was maintained between 55-60 mmHg by intravenous infusion of nitroglycerin (NTG) at a rate of 0.5-10 μg/kg/min. We recorded quality of surgical site [using average category scale (ACS)], the overall dose of NTG used, postoperative pain, the overall dose of mo.. View More»
DOI:
10.4172/2155-6148.1000789