Journal of Medical & Surgical Pathology
Open Access
ISSN: 2472-4971
ISSN: 2472-4971
Hideaki Iizuka
Japan
Case Report
Meningioma with Remarkable Multiple Rosette Formation: A Diagnostically Difficult Case
Author(s): Kenichi Mizutani, Satoko Nakada, Akira Tamase, Osamu Tachibana, Hideaki Iizuka, Takanori Hirose and Sohsuke YamadaKenichi Mizutani, Satoko Nakada, Akira Tamase, Osamu Tachibana, Hideaki Iizuka, Takanori Hirose and Sohsuke Yamada
Background: Rosette formation is a rare morphological feature in meningiomas. It can be seen in angiomatous, meningothelial, transitional, secretory, papillary or rhabdoid subtype; however there are very few reports of meningiomas with rosettes, and the feature itself is not criterion for the WHO grade, so this feature sometimes makes the diagnosis difficult.
Case presentation: A 62 y old Japanese woman stumbled and was admitted to a hospital. Magnetic resonance imaging showed a 50 mm extra-axial tumor on the right cerebral falx. Histologically, the tumor contained multiple rosettes that had a central nuclear-free zone without a vessel core. It also showed a sheet-like or whorled growth pattern and pseudopapillary structure. Some round tumor cells had abundantly dense eosinophilic cytop.. View More»
DOI:
10.4172/2472-4971.1000169