Chemotherapy: Open Access
Open Access

Hongyong Cao

Publications

• Review
  Landscape of Circular RNAs in the Clinical Application of Digestive System Neoplasm
  Author(s): Jian Zhou, Kai Fu, Yun Hu, Ran Qin, Lanxin Lin, Hongyong Cao and Wei-Wei Tang Jian Zhou, Kai Fu, Yun Hu, Ran Qin, Lanxin Lin, Hongyong Cao and Wei-Wei Tang
  
  It has been confirmed that noncoding RNAs (ncRNAs) play an important role in cellular development, differentiation, proliferation and apoptosis of various carcinomas. As a member of the ncRNAs family, circular RNAs (circRNAs) are getting new research hotspots because of their newly discovered and numerous potential functions such as acting as microRNA (miRNA) sponges and binding to RNA-binding proteins (RBPs) to modulate the gene transcription. Herein, we review the current understanding of the roles of circRNAs in the clinical application of digestive system neoplasm and provide a new insight into the potential implications in the diagnosis and targeted therapy of digestive system carcinomas. .. View More»
  DOI: 10.4172/2167-7700.1000251

  Abstract PDF

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