ISSN: 2155-6148
Huda Fahmy
Egypt
Research Article
Optic Nerve Sheath Diameter: An Ultrasonographic Window for Comparing between Hypertonic Saline and Mannitol in Severe Traumatic Brain Injuries
Author(s): Huda Fahmy, Amr Abdelaziz and Ayman Mohamady EldemrdashHuda Fahmy, Amr Abdelaziz and Ayman Mohamady Eldemrdash
Background: Clinically both mannitol and hypertonic saline (HTS) have been utilized successfully to manage elevated intracranial pressure (ICP), although which therapy is superior is yet unclear.Aim of the work: To compare the efficacy of hypertonic saline 3% and mannitol 20% in the reduction of increased intracranial pressure in sever traumatic brain injuries by ultrasonographic measurement of optic nerve sheath diameter (ONSD).Patient and methods: This prospective, double blind, randomized, observational, comparative study was performed on 30 patients who admitted to surgical intensive care unit in Aswan University Hospital with severe traumatized brain injury. All patients were examined by ultrasound to measure ONSD, we used a cut off value for ONSD as 5.5 mm to diagnose increase in ICP>20 mm Hg. Patients with signs .. View More»