Anesthesia & Clinical Research
Open Access

Humberto S Machado

Publications

• Review Article
  Perioperative Management of Patients with Down Syndrome: A Review
  Author(s): Mariana Brito Oliveira and Humberto S Machado Mariana Brito Oliveira and Humberto S Machado
  
  Introduction: Down syndrome (DS) or Trisomy 21 is associated with a higher morbidity, mortality and surgery need. This syndrome presents a characteristic set of morphologic features regarding several systems: cardiovascular, respiratory, gastrointestinal, nervous, musculoskeletal, immune, hematologic, endocrine, ophthalmic and hearing. Therefore, special care is required to maximize safety before, during and after surgery. This study’s objective is to systematically review these needs in the perioperative (pre, intra and postoperative) period, and how to approach them. Methods: PubMed and Web of Science were searched and 32 articles selected for this revision. Results: DS patients have commonly pulmonary arterial hypertension and congenital heart defects. They may have swallow function abnormalities or gastr.. View More»
  DOI: 10.4172/2155-6148.1000816

  Abstract PDF

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