ISSN: 2375-4397
+44 1223 790975
Hung-Hung Sung
Taipei 111
People's Republic of China
Research Article
Differential Expression of Physiological Genes of Neocaridina Denticulate at the Transcriptional Level Following Short-Term Exposure to Non-Lethal Concentrations of Phthalate Esters
Author(s): Su CH, Tsai YC and Hung-Hung SungSu CH, Tsai YC and Hung-Hung Sung
Xenobiotic phthalate esters (PAEs) are considered endocrine disrupting chemicals and are known to cause immunotoxicity, having been linked with the susceptibility of shrimp to pathogens; however, the effect on other physiological functions has not been explored. This study sought to understand the genetic responses of Neocaridina denticulate, a common freshwater shrimp, to three different PAEs, i.e., diethyl phthalate (DEP), dipropyl phthalate (DPrP), and diphenyl phthalate (DPP). The differential expression of 10 functional known expressed sequence tags derived from N. denticulate were analyzed by semi-quantitative RT-PCR after 24 h of exposure to non-lethal concentrations (0, 0.1, 1.0, and 10 mg/L) of PAEs in pond water. Compared with the control group, nine genes were differentially expressed in the DEP-treated groups, seven genes were differentially expressed in the DPrPt.. View More»
DOI:
10.4172/2375-4397.1000201