Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Hwang Kwon
Taiwan
Research Article
Day 4 Biopsy Improves Pregnancy Outcome Comparing to Day 3 Biopsy in Preimplantation Genetic Screening
Author(s): Eun-Kyung Kim, Eun-Ah Kim, Eun-Ha Kim, Nam-Hyung Kim, Dong-Hee Choi and Hwang Kwon
Eun-Kyung Kim, Eun-Ah Kim, Eun-Ha Kim, Nam-Hyung Kim, Dong-Hee Choi and Hwang Kwon
Aim: Preimplantation genetic screening (PGS) is a routine procedure performed in many in vitro fertilization (IVF) clinics. Embryo biopsy is an invasive procedure, and it has long been recognised that this procedure can affect the subsequent growth and development of the embryo.
Materials and methods: In total, 38 cycles from 31 couples were included in this study. Day 3 biopsy was performed on 126 embryos of 18 patients; 20 patients chose day 4 biopsy with 150 embryos tested. All specimens were screened on a 24-chromosome comparative genomic hybridization (CGH) array.
Results: Of the embryos subjected to day 3 and day 4 biopsies, 22.2% (28/126) and 28.7% (43/150) were normal, demonstrating that our biopsy system has no obvious detrimental effect on compaction. Embryos were transferred on the mornings of day 4 and .. View More»
DOI:
10.4172/2161-0932.1000330